human liver cancer cell line hepg2 (ATCC)
Structured Review

Human Liver Cancer Cell Line Hepg2, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 31283 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human liver cancer cell line hepg2/product/ATCC
Average 99 stars, based on 31283 article reviews
Images
1) Product Images from "Novel diazenyl chalcones with a 2-arylidene hydrazineylidene thiazole moiety: synthesis, anticancer potential, spectroscopic characterisation, and molecular docking studies"
Article Title: Novel diazenyl chalcones with a 2-arylidene hydrazineylidene thiazole moiety: synthesis, anticancer potential, spectroscopic characterisation, and molecular docking studies
Journal: RSC Advances
doi: 10.1039/d5ra07769a
Figure Legend Snippet: Fluorescent microscopy analysis of HepG2 cells treated with synthetic compounds (4–6a,b) and stained with acridine orange/ethidium bromide (AO/EB).
Techniques Used: Microscopy, Staining
Figure Legend Snippet: (A) Microscopic view of the cell migration inhibition assay of the HepG2 cell line after 48 hours. (B) Quantitative analysis of the wound area by calculating the wound closure percentage and migration rate after 48 hours, compared to the initial time (0 hours). (C) Relative fold change in the gene expression of MMP-2 and MMP-9 in cells treated with synthetic compounds (4–6a,b) in HepG-2. All assays were conducted in triplicate, and the results are expressed as mean ± SEM. MMP: matrix metalloproteinase.
Techniques Used: Migration, Inhibition, Gene Expression
Figure Legend Snippet: Structure–activity relationship (SAR) of the synthesised azo derivatives (4–6a,b) showing the effect of aromatic substitution on cytotoxic selectivity. Selectivity index (SI) values against MDA-MB-231 and HepG2 cells relative to WI-38 normal cells are shown.
Techniques Used: Activity Assay